Protein C is a major physiological anticoagulant. It is a vitamin K-dependent serine protease enzyme (EC 18.104.22.168) that is activated by thrombin into activated protein C (APC). The activated form (with protein S and phospholipid as a cofactor) degrades Factor Va and Factor VIIIa. It should not be confused with C peptide or c-reactive protein or protein kinase C.
Role in disease:
Protein C deficiency is a rare genetic disorder that predisposes to venous thrombosis and habitual abortion. If homozygous, this presents with a form of disseminated intravascular coagulation in newborns termed purpura fulminans; it is treated by replacing the defective protein C.
Send enquiry online
After send online enquiry, we will reply you as soon as possible, if not get any response on time please contact us by Tel or Email.
Tel: +86 592 5365887
WhatsApp: +86 189 6515 7632?